Thinking about taking a weight-loss drug like Ozempic? These are some of the pros and cons.

Large weight losses have been found in a more recent trial of semaglutide, suggesting weight loss is a very likely outcome of ongoing use of the medication.

2. It may reduce your chronic disease risk factors.

When people in the overweight or obese weight categories lose at least 5 per cent of their body weight, physiological changes often occur beyond a change in weight or shape. This might include lowered cholesterol levels, lowered blood pressure and lowered blood glucose levels, which all reduce the risk of chronic diseases.

In one of the semaglutide trials, most people (87.3 per cent) lost at least 5 per cent of their body weight. Although most of the large studies of semaglutide excluded people with metabolic health conditions such as type 2 diabetes, metabolic health gains were observed, including lowered blood pressure, blood glucose levels and fasting blood lipid (fat) levels.

In the UK study from 2021, people taking semaglutide had greater improvements in physical capabilities and risk factors for heart disease and diabetes, including reductions in waist circumference, markers of inflammation, blood pressure and blood glucose levels.

3. It might improve your quality of life, emotional wellbeing or sense of achievement.

The original trial of semaglutide did not focus on this bundle of benefits, but further follow-ups show additional benefits associated with the medication. Compared to the placebo, people taking semaglutide saw significant improvements in their physical functioning and perceptions of their general health, social functioning and mental health.